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APIs / Healthcare / Amazonaws / Amazon HealthLake
Amazon HealthLake logo

AWS Amazon HealthLake

Browse all Amazonaws APIs
60
AI ReadinessAI-Aware (B-)60/100
See full scorecard
Agent-ready OpenAPI document · curated by JenticHealthcareEhr Emrhmac13 EndpointsREST

Know of an official OpenAPI document? Contribute it →

For Agents

Provision and manage Amazon HealthLake FHIR datastores and orchestrate FHIR import and export jobs for bulk movement of healthcare data into AWS.

Use for: I need to create a new FHIR R4 datastore in HealthLake, Start a FHIR import job from an S3 bucket into a target datastore, Check the status of a recent FHIR export job, List all active FHIR datastores in this account

Not supported: Does not handle FHIR resource CRUD, clinical NLP, or appointment scheduling - use for HealthLake datastore provisioning and bulk import/export jobs only.

Jentic publishes the only available OpenAPI specification for Amazon HealthLake, keeping it validated and agent-ready. Amazon HealthLake is a HIPAA-eligible service that stores, transforms, queries, and analyses FHIR-formatted health data in the cloud. The control-plane API manages FHIR datastores and the import and export jobs that move bulk FHIR resources in and out of those datastores. With 13 operations it is a focused control surface for provisioning HealthLake infrastructure and running data movement jobs.

Jentic One on GithubView OpenAPI Document

Install Jentic One Beta

Connect the Amazon HealthLake to your agent

Jentic One is a self-hosted execution layer for AI agents. It lets your agent call the Amazon HealthLake, or any other public or private API you need. You set the rules, the agent never sees your credentials, and every call is logged.

Two steps, two machines. Install the instance in a safe environment, then register your agent from wherever it runs.

1

Step 1: Jentic One Host machine

# On the machine that will host your Jentic One instance:
curl -fsSL "https://jentic.com/install.sh?src=apis&api=%2Fapis%2Famazonaws.com%2Famazon-healthlake" | sh
2

Step 2: Agent machine

# On the machine where your agent runs (keep this separate from the instance):
curl -fsSL "https://jentic.com/install.sh?src=apis&api=%2Fapis%2Famazonaws.com%2Famazon-healthlake" | sh
jentic register       # connects your agent to your Jentic One instance

Jentic One is in public beta. The setup above keeps your agent separate from the instance, which is what you want before using real credentials: an agent running as the same OS user as Jentic One can read its stored keys directly. Just evaluating? A single local install is fine to start. See the secure deployment guide for the tiers.

Capabilities

What an agent can do with Amazon HealthLake API.

Create FHIR datastores configured for HIPAA-eligible workloads with optional SMART on FHIR support

Describe and list FHIR datastores filtered by status

Start FHIR import jobs that load bulk NDJSON data from S3 into a datastore

Start FHIR export jobs that write a datastore's resources to S3 in NDJSON

Cancel running export jobs and inspect their status

Tag HealthLake datastores and manage resource tags for cost allocation

Delete FHIR datastores and free associated storage when retention requirements allow

Use Cases

Patterns agents use Amazon HealthLake API for, with concrete tasks.

★ FHIR Data Lake Provisioning

Stand up a HIPAA-eligible FHIR R4 datastore for clinical research or population-health analytics. CreateFHIRDatastore provisions storage and a FHIR endpoint, optionally attaching SMART on FHIR for OAuth-style access and a KMS key for encryption. Once provisioned, the datastore endpoint is a fully compliant FHIR REST API.

Call CreateFHIRDatastore with DatastoreTypeVersion=R4, DatastoreName=research-prod, and a SseConfiguration referencing a customer-managed KMS key

Bulk EHR Migration to HealthLake

Migrate millions of FHIR resources from a legacy EHR or staging bucket into HealthLake using StartFHIRImportJob. The import reads NDJSON files from S3, transforms them into the datastore, and writes results back to a configured output bucket. DescribeFHIRImportJob and ListFHIRImportJobs surface progress and failures during the migration.

Call StartFHIRImportJob with InputDataConfig pointing at s3://my-fhir-staging/patients/ and JobOutputDataConfig pointing at s3://my-fhir-output/

Periodic Export for Analytics

Export FHIR resources on a schedule for downstream analytics in a data warehouse or ML pipeline. StartFHIRExportJob writes NDJSON to S3, and DescribeFHIRExportJob reports completion. This decouples analytical workloads from the live FHIR endpoint while still providing point-in-time data extracts.

Call StartFHIRExportJob with the DatastoreId and OutputDataConfig pointing at s3://analytics-fhir/exports/2026-06/

AI Agent Healthcare Operations

Through Jentic, an AI agent can orchestrate HealthLake provisioning and data movement as part of a wider healthcare workflow - for example, creating a research datastore, starting an import, and emitting a notification once it completes. Jentic exposes the 13 control-plane operations as discoverable tools.

Search Jentic for 'start fhir import job', load the StartFHIRImportJob schema, and execute it for a specified datastore and S3 input path

Key Endpoints

13 endpoints — jentic publishes the only available openapi specification for amazon healthlake, keeping it validated and agent-ready.

METHOD

PATH

DESCRIPTION

POST

/

CreateFHIRDatastore - provision a new FHIR datastore

POST

/

DescribeFHIRDatastore - fetch datastore configuration and status

POST

/

ListFHIRDatastores - list datastores in the account

POST

/

StartFHIRImportJob - bulk-load FHIR data from S3

POST

/

StartFHIRExportJob - export FHIR data to S3

POST

/

DescribeFHIRImportJob - check status of an import job

POST

/

DescribeFHIRExportJob - check status of an export job

POST

/

DeleteFHIRDatastore - delete a datastore and its resources

POST

/

CreateFHIRDatastore - provision a new FHIR datastore

POST

/

DescribeFHIRDatastore - fetch datastore configuration and status

POST

/

ListFHIRDatastores - list datastores in the account

POST

/

StartFHIRImportJob - bulk-load FHIR data from S3

POST

/

StartFHIRExportJob - export FHIR data to S3

POST

/

DescribeFHIRImportJob - check status of an import job

POST

/

DescribeFHIRExportJob - check status of an export job

POST

/

DeleteFHIRDatastore - delete a datastore and its resources

Jentic AI Readiness Score

This API is usable in Jentic One now. Its AI-readiness score against Jentic's framework shows where it stands today and where improvements would make it even easier for agents to use.

A

Amazon HealthLake

- AI-Aware (B-)
60/100
99
Foundational Compliance
63
Developer Experience & Jentic Compatibility
37
AI-Readiness & Agent Experience
94
Agent Usability
50
Security
100
AI Discoverability
Powered by JenticScoring Framework 1.0.0 | Scoring Engine 0.4.0
Show dimension breakdown
99

Foundational Compliance

Base layer of spec validity and structural soundness.

Grade: A+Signals: 4
98%

Lint Results

Aggregated quality score from linter diagnostics, weighted by severity.

100%

Resolution Completeness

Percentage of `$ref` references that resolve successfully.

100%

Specification Validity

Checks whether the API description parses successfully and conforms to its declared specification (e.g., OpenAPI).

100%

Structural Integrity

Structural correctness score based on schema issues using logarithmic dampening.

63

Developer Experience & Jentic Compatibility

Clarity, completeness, and ingestion readiness for developers and tooling.

Grade: B-Signals: 4
0%

Example Density

How richly the API is illustrated with examples.

100%

Example Validity

Percentage of examples that conform to their schemas.

50%

Response Coverage

Percentage of operations with complete response definitions (success, client error, server error).

100%

Tooling Readiness

Health of API ingestion, bundling, and resolution within Jentic pipelines.

37

AI-Readiness & Agent Experience

Semantic breadth, depth, and agent comprehension for AI systems.

Grade: FSignals: 4
47%

Description Coverage

Coverage of descriptions across API elements.

0%

Error Standardization

Coverage of RFC 9457 Problem Details for error responses.

100%

OperationId Quality

Coverage, uniqueness, and casing consistency of operationIds for AI inference.

0%

Summary Coverage

Coverage of summaries across operations/tags/info.

94

Agent Usability

Functional utility, complexity comfort, and AI orchestration readiness.

Grade: A+Signals: 1
94%

Complexity Comfort

Agent comfort level based on API operational and structural complexity.

50

Security

Trust, risk posture, and security compliance.

Grade: C-Signals: 1
50%

Authentication Strength

Average quality of security schemes based on authentication method strength (weakest link for OAuth2).

100

AI Discoverability

Findability, semantic richness, and reasoning readiness.

Grade: A+Signals: 1
100%

Descriptive Richness

Clarity and depth of descriptions across API elements.

View full reportHow the score is calculatedMore about the dimensions

Score it yourself

Every API in the directory is allowlisted, so you can re-score it with no key required.

Score your own APIScoring CLI agent skill
npx @jentic/api-scorecard-cli score <openapi-url>

Why Jentic?

What agents get from Jentic-routed access to this vendor.

Setup

Wiring Amazon HealthLake by hand means implementing AWS Signature v4 request signing, resolving the healthlake host, and dispatching each datastore and import/export action through one endpoint by the operation named in the request. Through Jentic you install once, import Amazon HealthLake from the API Directory, store the AWS credentials once, and your agent calls it.

Permission scoping

This API routes every call through a single endpoint with the action named in the request, covering operations like CreateFHIRDatastore, StartFHIRImportJob, and StartFHIRExportJob. Limit the agent to the operations it needs, such as DescribeFHIRDatastore and ListFHIRDatastores, so DeleteFHIRDatastore is not included unless you add it.

Credential isolation

Your AWS credentials are stored once, encrypted, by your own Jentic One instance and injected at execution time. They never enter the agent's prompt, logs, or context.

Intent-based discovery

Agents search Jentic by intent such as 'create a FHIR datastore' or 'start a bulk FHIR import from S3', and Jentic returns the matching Amazon HealthLake operation with its input schema so the agent calls the right endpoint without browsing the AWS service reference.

Related APIs

Alternatives and complements available in the Jentic catalogue.

Complementary

Amazon Comprehend

→

Comprehend Medical extracts clinical entities from unstructured notes that can be loaded into HealthLake

Use Comprehend Medical to convert free-text clinical notes into structured entities, then load them into HealthLake; HealthLake itself stores the structured FHIR result.

Complementary

Amazon SageMaker

→

Train and deploy ML models on FHIR data exported from HealthLake

Use SageMaker for training models on healthcare data; use HealthLake to store and version the underlying FHIR resources.

Complementary

AWS CloudTrail

→

Audit log of every HealthLake control-plane API call for compliance

Use CloudTrail to audit who created or deleted HealthLake datastores; HealthLake itself does not retain that activity history.

FAQs

Specific to using Amazon HealthLake API through Jentic.

Why is there no official OpenAPI spec for Amazon HealthLake?

AWS does not publish an OpenAPI specification. Jentic generates and maintains this spec so that AI agents and developers can call Amazon HealthLake via structured tooling. It is validated against the live API and kept up to date. Get started with Jentic One, the self-hosted execution layer.

What authentication does the Amazon HealthLake API use?

The control-plane API uses AWS Signature Version 4 (HMAC) request signing with an AWS access key ID and secret access key. The FHIR data-plane endpoint on a datastore uses SigV4 by default and optionally SMART on FHIR OAuth tokens.

Can I import bulk FHIR data with the Amazon HealthLake API?

Yes. Call StartFHIRImportJob with an InputDataConfig that points to S3 NDJSON files and a JobOutputDataConfig for results. Use DescribeFHIRImportJob to monitor progress and inspect failed resources.

What are the rate limits for the Amazon HealthLake API?

AWS applies per-account, per-region request quotas to HealthLake control-plane operations and these vary by call. Datastore creation has lower quotas than describe and list operations. Check AWS Service Quotas for current limits.

How do I create a HealthLake datastore through Jentic?

Search Jentic for 'create healthlake fhir datastore', load the CreateFHIRDatastore schema, and execute with DatastoreTypeVersion=R4, a DatastoreName, and an optional KMS SseConfiguration. The response includes the DatastoreEndpoint URL once status reaches ACTIVE.

Is Amazon HealthLake HIPAA-eligible?

Yes. HealthLake is a HIPAA-eligible service and customers can use it for protected health information under a Business Associate Addendum with AWS. Encryption at rest with KMS and TLS in transit is enforced by default.

Can I limit what my agent is allowed to do with the AWS HealthLake API?

Yes. Because you run Jentic One yourself, your own rules decide which HealthLake operations the agent may call, even though every request goes through a single endpoint with the action named in the request. You can allow read-only operations such as DescribeFHIRDatastore and ListFHIRDatastores while withholding write actions like CreateFHIRDatastore, StartFHIRImportJob, and StartFHIRExportJob. DeleteFHIRDatastore stays out of reach unless you explicitly add it, and the AWS credentials the agent uses are supplied by your instance at execution time rather than exposed to the agent.

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