Infermedica API
Official vendor OpenAPI document · agent-readyHealthcareClinical DataapiKey16 EndpointsREST
For Agents
Run adaptive symptom-check interviews, get triage recommendations, parse free-text symptoms into coded concepts, and look up clinical concepts (symptoms, conditions, risk factors, lab tests).
Use for: I want to start a symptom-check interview for a 35-year-old female with abdominal pain, Get the next question Infermedica recommends asking the patient, Check whether the reported symptoms include any emergency red flags, Retrieve the triage level for a given evidence set
Not supported: Does not handle EHR record storage, prescription writing, or appointment scheduling - use for symptom checking, differential diagnosis, triage, and medical concept lookup only.
Infermedica is an AI-powered clinical decision support API for symptom checking, differential diagnosis, and patient triage. The 16-endpoint v3 API runs adaptive diagnostic interviews via /diagnosis, recommends triage levels (emergency, consultation, self-care) via /triage, parses free-text patient complaints into coded symptoms via /parse, and exposes structured medical concept catalogues for symptoms, conditions, risk factors, and lab tests. Authentication uses a paired App-Id and App-Key header credential model, allowing partners to track usage per integration.
Install Jentic One Beta
Connect the Infermedica API to your agent
Jentic One is a self-hosted execution layer for AI agents. It lets your agent call the Infermedica API, or any other public or private API you need. You set the rules, the agent never sees your credentials, and every call is logged.
Two steps, two machines. Install the instance in a safe environment, then register your agent from wherever it runs.
1
Step 1: Jentic One Host machine
# On the machine that will host your Jentic One instance:
curl -fsSL "https://jentic.com/install.sh?src=apis&api=%2Fapis%2Finfermedica.com%2Finfermedica" | sh2
Step 2: Agent machine
# On the machine where your agent runs (keep this separate from the instance):
curl -fsSL "https://jentic.com/install.sh?src=apis&api=%2Fapis%2Finfermedica.com%2Finfermedica" | sh
jentic register # connects your agent to your Jentic One instanceJentic One is in public beta. The setup above keeps your agent separate from the instance, which is what you want before using real credentials: an agent running as the same OS user as Jentic One can read its stored keys directly. Just evaluating? A single local install is fine to start. See the secure deployment guide for the tiers.
Capabilities
What an agent can do with Infermedica API.
Run an adaptive diagnostic interview where each call to /diagnosis returns either the next clarifying question or a ranked condition list
Recommend a triage level - self-care, consultation, or emergency - for a given symptom set via /triage
Parse free-text patient narratives into structured Infermedica concept IDs via /parse
Suggest related symptoms a patient might also have via /suggest, improving interview completeness
Surface emergency red flags from a symptom set with /red_flags before making the user wait through a full interview
Look up structured catalogues of symptoms, conditions, risk factors, and lab tests with the /symptoms, /conditions, /risk_factors, and /lab_tests endpoints
Search the medical concept graph by free text with /search and explain a diagnosis result with /explain
Use Cases
Patterns agents use Infermedica API for, with concrete tasks.
★ Patient-Facing Symptom Checker
Power a symptom-checker chatbot or web app where a patient describes how they feel and the application asks adaptive follow-up questions before showing likely conditions and a triage recommendation. Each turn calls POST /diagnosis with the running evidence list; Infermedica returns either the next question or a stop signal with the differential. POST /triage returns the recommended care level.
Call POST /diagnosis with sex='female', age=35, and an evidence array containing symptom 's_21' (abdominal pain), then return the next recommended question.
Free-Text Intake Parsing
When a patient types 'I've had a headache and nausea for two days', POST /parse converts that to Infermedica concept IDs (e.g., s_98 for headache, s_156 for nausea), so a downstream /diagnosis call has structured evidence. Useful for chat-based intake flows and EHR free-text fields where humans describe symptoms in natural language.
POST /parse with text 'severe headache and nausea since yesterday' and return the extracted Infermedica concept IDs.
Emergency Triage Pre-Check
Before running a full diagnostic interview, POST /red_flags evaluates whether the symptom set already contains a clinical red flag that warrants immediate emergency triage - for example, chest pain with shortness of breath. This shortcut lets a triage app escalate to 'go to emergency department' without making the user answer 20 questions first.
POST /red_flags with evidence containing chest pain and shortness of breath; if any red flag is returned, route the user to emergency triage immediately.
AI Healthcare Agent
An LLM agent acting as a virtual medical assistant uses Infermedica as its grounded clinical reasoning tool. Through Jentic, the agent searches by intent (e.g., 'run a symptom check'), loads the schema, and calls /parse, /diagnosis, /red_flags, and /triage in sequence. This keeps clinical reasoning anchored to a regulated medical knowledge base rather than hallucinated by the LLM.
Parse a free-text complaint with /parse, run /diagnosis to convergence, then call /triage on the final evidence set and return the recommended care level.
Key Endpoints
16 endpoints — infermedica is an ai-powered clinical decision support api for symptom checking, differential diagnosis, and patient triage.
METHOD
PATH
DESCRIPTION
POST
/diagnosis
Run a step of the adaptive diagnostic interview
POST
/triage
Get a triage level for the current evidence
POST
/parse
Parse free-text symptoms into concept IDs
POST
/red_flags
Detect emergency red flags in the evidence set
POST
/suggest
Suggest related symptoms to ask about
GET
/symptoms
List all symptoms in the catalogue
GET
/conditions
List all conditions in the catalogue
GET
/search
Free-text search across the medical concept graph
POST
/diagnosis
Run a step of the adaptive diagnostic interview
POST
/triage
Get a triage level for the current evidence
POST
/parse
Parse free-text symptoms into concept IDs
POST
/red_flags
Detect emergency red flags in the evidence set
POST
/suggest
Suggest related symptoms to ask about
GET
/symptoms
List all symptoms in the catalogue
GET
/conditions
List all conditions in the catalogue
GET
/search
Free-text search across the medical concept graph
Why Jentic?
What agents get from Jentic-routed access to this vendor.
Setup
Wiring the Infermedica API by hand means sending its paired App-Id and App-Key headers on every call and mapping its diagnosis, triage, and lookup endpoints yourself. Through Jentic you install once, import the Infermedica API from the API Directory, store both header values once, and your agent calls it.
Permission scoping
Infermedica takes the evidence and patient context in the request body rather than the URL path, so limit the agent to the operations it needs, such as running a symptom check or fetching a triage level. You choose which operations are allowed, so the free-text parse and suggest endpoints are not included unless you add them.
Credential isolation
Your Infermedica App-Id and App-Key are stored once, encrypted, by your own Jentic One instance and injected at execution time. They never enter the agent's prompt, logs, or context.
Intent-based discovery
Agents search Jentic by intent such as 'run a symptom check' or 'get a triage level', and Jentic returns the matching Infermedica operation with its input schema so the agent learns the diagnosis evidence shape without browsing the medical-domain docs.
Related APIs
Alternatives and complements available in the Jentic catalogue.
Complementary
Stripe API
Stripe processes payments and subscriptions for telehealth services that Infermedica triages.
Use Stripe alongside Infermedica when the symptom checker leads into a paid consultation booking and you need to charge the patient or insurer.
FAQs
Specific to using Infermedica API through Jentic.
What authentication does the Infermedica API use?
The Infermedica API uses paired App-Id and App-Key headers - both are required on every request. Through Jentic, both credentials are stored encrypted in your Jentic One instance and injected at execution time so the agent never holds either raw value.
Can I parse free-text symptoms into Infermedica concept IDs?
Yes. POST /parse takes a free-text narrative (e.g., 'severe headache and nausea since yesterday') and returns Infermedica concept IDs and the surface text that mentioned them, ready to drop into the evidence list for /diagnosis or /triage.
What are the rate limits for the Infermedica API?
Rate limits depend on the partnership tier - sandbox accounts have low limits, and production limits are negotiated with Infermedica during integration. Check developer.infermedica.com or your partnership agreement for exact ceilings.
How do I run a symptom check through Jentic?
Search Jentic for 'run a symptom check' to find POST /diagnosis. Load the schema (sex, age, evidence array), execute, and call /diagnosis again with each new answer until 'should_stop' is true. Then call POST /triage on the same evidence. Get started with Jentic One, the self-hosted execution layer.
Does the API include emergency red flag detection?
Yes. POST /red_flags evaluates an evidence set against Infermedica's red-flag rules and returns the matching flags so a triage application can escalate to emergency care without completing a full interview. Use this as a safety pre-check on any symptom-check flow.
Is Infermedica suitable for clinical or only consumer applications?
Infermedica is used in both. The same v3 API powers patient-facing symptom checkers and call-centre triage tools. Regulatory clearance and intended-use disclaimers depend on the deployment market - Infermedica's compliance team works with partners on CE marking and FDA pathways.
Can I limit what my agent is allowed to do with the Infermedica API?
Yes. Because Jentic One is self-hosted, you decide which Infermedica operations your agent may call, so you can allow just the ones it needs, such as running a symptom check with POST /diagnosis or fetching a care level with POST /triage. Since Infermedica passes evidence and patient context in the request body rather than the URL path, scoping happens at the operation level: the free-text POST /parse and POST /suggest endpoints stay off unless you explicitly add them. Your paired App-Id and App-Key are held only by your own instance and injected at execution time, so the agent works within the operations and credentials your rules permit.
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